Price:
60 count bottle: $23.98

Description:
CranXact® is a proprietary cranberry plant extract that helps prevent bacteria from adhering to the wall of the urinary tract, stomach and mouth. It is patented to provide the highest levels of bacteria anti-adhesion activity.

Who should take CranXact?
Anyone prone to developing high levels of bacteria in their urinary tract where bacteria can stick to epithelial tissue and gradually colonize and multiply over time. Inhibiting this build-up is very important to the urinary tract's long term health.

How does CranXact work?
CranXact contains natural plant extracts which inhibit bacteria from sticking to the bladder wall, so they are naturally flushed from the body during urination. It is not an antibiotic. It does not kill bacteria. Therefore, it does not have any of the side effects of antibiotics, such as compromising the immune system by destroying friendly bacteria (sometimes leading to yeast infections) or creating antibiotic resistant bacteria. Rather, it helps maintain healthy microflora. Evidence is growing that this bacteria anti-adhesion mechanism of action may also apply to the build-up of bacteria in the oral cavity and to H.pylori in the stomach.

Receptor sites on bacteria pili bind to the bladder wall. Bacteria can then adhere, colonize and multiply.

The active ingredients in CranXact bind to the E-coli pili helping to prevent bacteria from adhering to the bladder. Bacteria can then be safely flushed from the body during urination.

Is CranXact superior to other Cranberry Supplements?

• CranXact is the result of over 20 years of research and development.
  
• This research resulted in a highly potent cranberry supplement and the only product of its kind to be awarded four U.S. patents for its bacteria anti-adhesion research and results.
  
• CranXact is highly concentrated in bacteria anti-adhesion activity compared to other major cranberry supplements on the market.

NOTICE: This product is not a substitute for antibiotics for acute infections.

**Patent #'s 5,474,774 ; 5,525,341 ; 5,646,178 ; and 5,650,432 . Based on red blood cell hemagglutination assay.

Brochures:
download a .pdf brochure - 670 KB
download a .pdf white paper  - 22 KB
download a .pdf clinical reference guide - 22 KB
download a .pdf product spec sheet - 313 KB

Studies:
Studies of bacteria anti-adhesion of urinary tract, oral cavity and stomach.

1. Sobota AE. Inhibition of bacterial adherence by cranberry juice: Potential use for the treatment of urinary tract infections. J Urol 1984;131:1013–6.
2. Zafriri D, Ofek I, Adar R, et al. Inhibitory activity of cranberry juice on adherence of type 1 and type P fimbriated Escherichia coli to eucaryotic cells. Antimicrob Agents Chemother 1989;33:92–8.
3. Gibson L, Pike L, et al. Effectiveness of Cranberry Juice in Preventing Urinary Tract Infections in Long-term Care Facility Patients. J Naturopathic Med. 1991;2:45-47.
4. Avorn J, Monane M, Gurwitz JH, et al. Reduction of bacteriuria and pyruria after ingestion of cranberry juice. JAMA 1994;271:751–4.
5. Nazarko L. Infection Control. The Therapeutic Uses of Cranberry Juice. Nurs Stand. 1995;9(34):33-35.
6. Leaver RB. Cranberry juice. Prof Nurse 1996;11:525–6 [review].
7. Howell AB, Vorsa N, Der Maderosian A. Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial—all surfaces by proanthocyanidin extracts from cranberries. New Engl J Med 1998;339:1005–6.
8. Walker EB, Barney DP, Mickelsen JN, et al. Cranberry concentrate: UTI prophylaxis. J Family Pract 1997;45:167–8 [letter].
9. Schlager TA, Anderson S, Trudell J, Hendly JO. Effect of cranberry juice on bacteriuria in children with neurogenic bladder receiving intermittent catheterization. J Pediatr 1999; 135:698–702.
10. Lynch DM. Cranberry for prevention of urinary tract infections. Am Fam Physician. 2004 Dec 1;70(11):2175-7
11. Jepson RG. Cranberries for preventing urinary tract infections. Cochrane Database Syst. Rev. 2004;(2):CD001321
12. Weiss EI, Lev-Dor R, Kashamn Y, Goldhar J, Sharon N, Ofek I. Inhibiting Interspecies coaggregation of plaque bacteria with cranberry juice constituent. JADA, 1998. 129:1710-1723.

Directions:
As a dietary supplement, take one capsule in the morning and one capsule in the evening with food or a glass of water.  Store in a cool, dry place.

Ingredients:

Serving Size: 1 capsule
Servings Per Container: 60
Amount Per Serving		% DV
CranXact® Proprietary Blend. A blend of the following two extracts:	180 mg	-
Proprietary Extract Blend #1: Cranberry (seeds), Apple (skins, seeds, fruit)	90mg	-
Proprietary Extract Blend #2: Grape (seeds), Apple (skins, seeds, fruit), Cranberry (fruit and/or seeds)	90mg	-
* Daily Value (DV) not established